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To understand whether prediction of preeclampsia can be improved by adding study of maternal heart parameters

Role of maternal cardiovascular markers in predicting adverse outcomes in women with Pre eclampsia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/03/064329
Enrollment
128
Registered
2024-03-18
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O14- Pre-eclampsia

Interventions

Intervention1: Nil: Nil

Sponsors

AIIMS New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Pregnant women admitted with diagnosis of PE at gestational age lesser than or equal to 34 weeks according to ISSHP criteria 2. Willing to be part pf study

Exclusion criteria

Exclusion criteria: 1. Presence of fetal chromosomal or structural abnormality 2. Maternal cardiac disease 3. Hematological disorders 4. Multifetal gestation 5. Pre existing chronic hyertension

Design outcomes

Primary

MeasureTime frame
Maternal core outcomes A) Clinical parameters 1. Maternal mortality 2. Eclampsia 3. Stroke 4. Cortical blindness 5. Retinal detachment 6. Pulmonary edema 7. Acute kidney injury 8. Liver capsule hematoma or rupture 9. Placental abruption 10. Post partum haemorrhage 11. Admission to Intensive care unit requiring intubation or mechanical ventilation (not for childbirth) Perinatal outcomes 1. Stillbirth 2. Gestational age at delivery 3. Birthweight 4. Small for gestational age 5. Neonatal mortality 6. Neonatal seizures 7. Admission to Neonatal unit required 8. Respiratory support required Timepoint: Following initial assessment patient will be followed up and managed according to institutional protocol till 7 days postpartum—

Secondary

MeasureTime frame
1. Predictive ability of FullPIERS model for adverse maternal and perinatal outcomes in women with Pre eclampsia 2. Predictive ability of sFLT/PlGF ratio with or without uterine artery doppler for adverse maternal and perinatal outcomes in women with Pre eclampsia 3. Development of a multiparametric model integrating clinical, biochemical, placental and maternal cardiovascular markers for predicting adverse outcomes in women with Pre eclampsiaTimepoint: Following initial assessment, patient will be followed up and managed according to institution protocol till 7 days postpartum—

Countries

India

Contacts

Public ContactDr Niharika Kumari

AIIMS New Delhi

kaparnasharma@gmail.com9711824415

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026