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A study comparing pain levels after using different root canal sealers along with newer file systems in multi-visit endodontic therapy

A comparative evaluation of postoperative pain perception using three different root canal sealers along with contemporary file systems in multi-visit endodontic therapy: A randomized controlled trial. - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/03/064304
Enrollment
112
Registered
2024-03-18
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis Health Condition 2: K044- Acute apical periodontitis of pulpal origin

Interventions

Intervention1: Group B2(Protaper ultimate and Calcium silicate based sealer): The multivisti root canal treatment procedure in which the included cases in the second group will undergo biomechanical t

Sponsors

All India Institute of Medical Sciences, Bathinda
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 18?50 years who presented with no systemic disease (American Society of Anesthesiology class I) and requires nonsurgical root canal treatment. Mandibular 1st molar. Diagnosis of symptomatic apical periodontitis with irreversible pulpitis in a molar tooth with independent root canals. Tooth with Class 1 occlusal caries. Patients using smartphone for easy communication and to maintain regular follow up.

Exclusion criteria

Exclusion criteria: Medically compromised patients (with immunosuppressive/systemic diseases, patients on medications, pregnant/lactating mothers. Cracked or unrestorable teeth, teeth with periodontal probing depths 4 mm or more, had incomplete root formation, Peri apical index (PAI) score not more than 4. Tooth with severe root curvature, dilacerated, incomplete root formation and other root deformities. Sinus tract, calcified canals.

Design outcomes

Primary

MeasureTime frame
Clinical Outcome Comparison of pain reduction on the three arms of treatment. Removal of infected and necrotic pulp. Timepoint: 24hours,48hours,7days

Secondary

MeasureTime frame
Patient-centred Outcome Healing of the periapical infection. Restoration of carious tooth form and function. Timepoint: 24hrs,48hrs, 7 days

Countries

India

Contacts

Public ContactDr Ashish J Johnson

All India Institute of Medical Sciences, Bathinda

drtarunkumarsingh@gmail.com9560627466

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026