A CLINICAL TRIAL TO STUDY AND COMPARE THE EFFECTS OF LASER AND FERULIC ACID CHEMICAL PEEL IN THE OF TREATMENT OF A SKIN DISEASE CALLED ACANTHOSIS NIGRICANS WHICH IS CHARACTERIZED BY DIRTY HYPERPIGMENTATION OF NECK .

A COMPARATIVE STUDY OF FRACTIONAL CO2 LASER VERSUS FERULIC ACID SEQUENTIAL (12% & 8%) PEEL IN THE TREATMENT OF NECK ACANTHOSIS NIGRICANS. - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/064291

Enrollment

Registered

2024-03-18

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: PCS- Health Condition 2: L83- Acanthosis nigricans

Interventions

Intervention1: Fractional co2 laser vs Ferulic acid sequential peel 12% and 8%: Fractional co2 laser for 4 sittings at 2 weeks interval Ferulic acid sequential peel 12% and 8% for 4 sittings at 2 we

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients of both the sexes with neck acanthosis nigricans

Exclusion criteria

Exclusion criteria: 1.Patients with recent history of any topical treatment and any procedures for neck acanthosis nigricans at least 1month before enrolment into the study. 2.Patients who received systemic retinoids six months prior to the start of study. 3.Patients with skin infection of the neck at the time of the session. 4.Patients with keloidal tendency. 5.Pregnant or lactating women.

Design outcomes

Primary

Measure	Time frame
To evaluate the efficacy of fractional co2 laser and ferulic acid sequential peel (12% and 8%) in the treatment of neck acanthosis nigricans. It is assessed by ANASI score system. visual analogue scale (scoring from 0 to 10) Timepoint: Baseline, 2 weeks once follow up for 2months.	—

Secondary

Measure	Time frame
To document the post procedural side effects of fractional co2 laser & ferulic acid sequential peel (12% & 8%) in the treatment of neck acanthosis nigricans. The Global Photograph Assessment (GPA)scale. The visual discomfort scale (scoring from 0 to 10)Timepoint: Baseline ,once in 2weeks follow up for 2months.	—

Countries

India

Contacts

Public ContactDr Akshata Yadav S

Sri Devaraj Urs Academy Higher Education and Research

abhishekhv03@gmail.com9632962335

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026