Health Condition 1: T604- Toxic effect of rodenticides
Conditions
Interventions
Intervention1: Injection N Acetyl Cysteine: N Acetyl cysteine
(150mg/kg in 200ml of 5 % dextrose over 15 min then 50mg/kg in 500 ml of
5% dextrose over 4 hours then 100mg/kg of 1L of 5 % dextrose over
Sponsors
J.L.N Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: All patients with history of rodenticide poisoning with zinc phosphide in Emergency OPD Patient willing for study
Exclusion criteria
Exclusion criteria: Patient not willing for study Poisoning with unknown compound Patient less than 18 years of age and more than 70 years If zinc phosphide mixed with other poisons but not limited to alcohol Patient has preexisting liver pathology which includes acute/chronic hepatitis before ingestion. Patient has preexisting renal pathology which includes acute chronic renal failure before ingestion. History of psychiatric illness History of respiratory or cardiac diseases History of epilepsy or bleeding tendencies Treatment initiated before arriving to the emergency OPD
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study the efficacy of N acetyl cysteine in management of zinc phosphide rodenticide poisoning in reducing morbidity and mortality in patientsTimepoint: zero hrs at time of admission 12hrs 24hrs 48hrs 72hrs | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess biochemical outcomes Cardiac outcome with serial ECG studies To compare morbidity and mortality outcomesTimepoint: 0hrs 12hrs 24hrs 48hrs 72hrs | — |
Countries
India
Contacts
Public ContactDr Siva K V
J.L.N Medical College Ajmer
Outcome results
None listed