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Comparing the effect of tranexamic acid needling versus tranexamic acid injections in melasma

Split face study comparing efficacy of microneedling with tranexamic acid versus microinjections with tranexamic acid in melasma in Indian skin - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/03/064275
Enrollment
60
Registered
2024-03-18
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L818- Other specified disorders of pigmentation

Interventions

Intervention1: Microneedling with with tranexamic acid in the treatment of melasma: For patients with melasma microneedling with tranexamic acid given at baseline then every 2 weeks for a maximum of

Sponsors

Vinayaka Missions Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with clinical diagnosis of melasma Patients who are willing to participate in the study

Exclusion criteria

Exclusion criteria: Patients allergic to Tranaxemic acid Patients with predisposition to keloids Pregnant and lactating mothers Patients with history of bleeding disorders use of oral anticoagulant drugs Patients under oral contraceptive pills hormonal replacement therapy at the time of or during the past 12 months of study Patients with a history of treatment for melasma in the past 6 weeks in any form

Design outcomes

Primary

MeasureTime frame
Compare the clinical response by mMASI and PtGA score to microneedling with tranexamic acid and microinjections with tranexamic acid in treatment of melasma Timepoint: every 2 weeks for 3 months, and at the end of 6 months

Secondary

MeasureTime frame
Treatment side effectsTimepoint: Every 4 weeks for 3 months and at the end of 6 months

Countries

India

Contacts

Public ContactDr V JAYAMALIGA

VINAYAKA MISSIONS MEDICAL COLLEGE KARAIKAL

hoddvdvmmckkl@gmail.com9884835199

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026