Comparison between new and old surgical technique for donor eye collection

A multicentric randomised control trial comparing percentage of optical grade donor human corneas and endotheial cell density between traditional and modified corneoscleral rim excision techniques- a surgical technique trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/064249

Enrollment

500

Registered

2024-03-15

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Donor Corneoscleral Rim excision by Traditional Technique: Traditional Technique involves the use of NO drug in the anterior chamber before the excision of the Donor rim. This is a sing

Eligibility

Inclusion criteria

Inclusion criteria: 1. All Corneas Harvested from Eye Bank 2. Consecutive recruitment 3. Death to collection time less than 6 hours (with or without body cooling)

Exclusion criteria

Exclusion criteria: 1. Death to collection time more than 6 hours 2. Accidental injury during tissue transport 3. Improper harvesting technique 4. Vitreous loss during collection of tissue

Design outcomes

Primary

Measure	Time frame
Endothelial Cell density on sepcular MicroscopyTimepoint: 1. Post Harvesting Day 1	—

Secondary

Measure	Time frame
Area of cellTimepoint: 1. Post Harvesting Day 1;No Of Cells CountedTimepoint: 1. Post Harvesting Day 1;No of Rejected tissues I vs IITimepoint: 1. Post harvesting day 4 2. Post Harvesting Day 14;Percentage HexagonalityTimepoint: 1. Post Harvesting Day 1;Rejected Tissues vital cell analysisTimepoint: 1. Post Harvesting Day 4 2. 1. Post Harvesting Day 15	—

Countries

India

Contacts

Public ContactDr Charuta J Puranik

Oculus Regenerus Eye Care and Research Center

charuta.j.p17@gmail.com9819473633

Outcome results