A comparative study of two different opioids in two different routes for postoperative analgesia in patients undergoing major abdominal surgeries

A comparative study between transdermal buprenorphine patch versus intravenous fentanyl for postoperative analgesia in patients undergoing major abdominal surgeries under general anaesthesia

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/064238

Enrollment

Registered

2024-03-15

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: transdermal buprenorphine patch 5mcg/H: applied over hairless areas for 3 days post operatively Control Intervention1: Intravenous fentanyl: 25mcg every 6th hourly for 3 days postoperat

Eligibility

Inclusion criteria

Inclusion criteria: Patients with weight 40-80kgs. Patients scheduled for open elective intraperitoneal abdominal surgeries under general anaesthesia Patients giving informed written consent. Patients belonging to ASA I, II.

Exclusion criteria

Exclusion criteria: 1.Patients who refused to give informed written consent. 2.Patients with ASA physical status III or more. 3.Patients with known cardiac and pulmonary complications. 4.Patients with known allergy to opioids. 5.Patients with mental illness. 6.Pregnants and breastfeeding females. 7. Surgeries of duration > 3 hours. 8. Surgeries including surgical incision extended 5 cm above the umbilicus.

Design outcomes

Primary

Measure	Time frame
visual analogue scale Timepoint: Post operative day 1 to day 3	—

Secondary

Measure	Time frame
ramsay sedation scale hemodynamic parameters adverse effectsTimepoint: post operative day 1 to 3	—

Countries

India

Contacts

Public ContactDr Asha N

bangalore medical college and research institute

ashamshu@gmail.com9900622335

Outcome results