Comparison between two different routes of administering Mitomycin C drug during Glaucoma surgery

Comparative study of Surgical Outcomes of Mitomycin C - sponge application versus subconjunctival injection during Trabeculectomy - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/064178

Enrollment

Registered

2024-03-15

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H401- Open-angle glaucoma

Interventions

Intervention1: subconjunctival injection: intraoperative 0.4 mg/ml subconjunctival injection of Mitomycin C during Trabeculectomy with a 30G needle, 7-8 mm away from limbus Control Intervention1: spon

Eligibility

Inclusion criteria

Inclusion criteria: Above the age of 18 years

Exclusion criteria

Exclusion criteria: 1) High myopia 2) Thin sclera 3) Refractory glaucoma 4) loss to follow up

Design outcomes

Primary

Measure	Time frame
Post operative intraocular pressureTimepoint: on day 1 of admission, on the day of surgery post-operative after 1 week, 1month, 3months	—

Secondary

Measure	Time frame
Need of post of any post operative interventionsTimepoint: on day 1 of admission, on the day of surgery post-op after 1 week, 1month, 3months;Number of Anti Glaucoma medications required after surgeryTimepoint: on day 1 of admission, on the day of surgery post-op after 1 week, 1month, 3months;Post operative complications: bleb leak/ hypotony/ shallow AC/ infection/ corneal hazeTimepoint: on day 1 of admission, on the day of surgery post-op after 1 week, 1month, 3months	—

Measure

Time frame

Need of post of any post operative interventionsTimepoint: on day 1 of admission, on the day of surgery post-op after 1 week, 1month, 3months;Number of Anti Glaucoma medications required after surgeryTimepoint: on day 1 of admission, on the day of surgery post-op after 1 week, 1month, 3months;Post operative complications: bleb leak/ hypotony/ shallow AC/ infection/ corneal hazeTimepoint: on day 1 of admission, on the day of surgery post-op after 1 week, 1month, 3months

—

Countries

India

Contacts

Public ContactAboli Chikhalikar

Sankara eye hospital Guntur

malleswari6372@gmail.com9751945985

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026