To compare the effects of sugammadex and neostigmine as an effective reversal agent for muscle relaxation in children undergoing abdominal and urogenital surgeries under general anaesthesia .

Comparative analysis of sugammadex versus neostigmine as an effective reversal agent in paediatric abdominal and urogenital surgeries under general anaesthesia. A randomised control study. - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/064171

Enrollment

Registered

2024-03-15

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Sugammadex: Injection Sugammadex 2mg per kg body weight single dose slow iv to be administered at the reappearance of T2 on train of four stimulation after completion of surgery and to

Eligibility

Inclusion criteria

Inclusion criteria: Abdominal surgeries Urogenital surgeries ASA 1&2 General anaesthesia

Exclusion criteria

Exclusion criteria: Not willing for consent Developmental delay Known history of drug allergy Diseases affecting neuromuscular junction or malignant hyperthermia Kidney / liver failure

Design outcomes

Primary

Measure	Time frame
Time from start of administration of sugammadex/ neostigmine to recovery of the T4/T1 ratio to 0.9Timepoint: At reappearance of T2	—

Secondary

Measure	Time frame
Number of participants with clinical signs of recovery assessed by GCS and MRC.Timepoint: At intervals of 15 mins, 30 mins, 1 hr and 2 hrs in Post anaesthesia care unit.	—

Countries

India

Contacts

Public ContactDr. Subrata Kumar Singha

All India Institute of Medical Sciences, Raipur

subratsingh@gmail.com8518881767

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026