Comparison of ratio of blood components in pyorrhea patients before and after treatment.

Comparative evaluation of Neutrophil-to- Lymphocyte Ratio (NLR) and Platelet to Lymphocyte Ratio (PLR) in chronic periodontitis patients before and after surgical periodontal therapy- An interventional study - nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/064169

Enrollment

104

Registered

2024-03-14

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Periodontal Flap Surgery. Comparator agent not applicable for single arm study.: Plaque index, Gingival index, Modified sulcus bleeding index, Probing pocket depth, Clinical Attachment

Eligibility

Inclusion criteria

Inclusion criteria: Minimum of 20 teeth to be present in every patient and minimum 4 teeth present in each quadrant Cases of stage three periodontitis CAL greater than or equal to 5mm and PPD greater than or equal to 6mm

Exclusion criteria

Exclusion criteria: Patients suffering from known systemic diseases and known allergy Pregnant, lactating and menopause female patients Patients with habit of any form of tobacco Patients who have received any antibiotic and or anti-inflammatory drug therapy during past 3 months Patients who received surgical or nonsurgical periodontal therapy in last 6 months Patients with autoimmune diseases Patients with any systemic/ hematologic disorder Patients with history of fever in last 1 month

Design outcomes

Primary

Measure	Time frame
Change in Neutrophil to Lymphocyte ratio and Platelet to Lymphocyte ratio after surgical periodontal therapy in chronic periodontitis patientsTimepoint: 10 weeks	—

Secondary

Measure	Time frame
Change in Plaque index (PI) (Silness & Loe, 1964) Gingival Index (GI) (Loe & Silness, 1963) Modified Sulcus Bleeding Index (Mombelli et al, 1987) PROBING POCKET DEPTH(PPD) CLINICAL ATTACHMENT LEVEL(CAL) Timepoint: 10 weeks	—

Countries

India

Contacts

Public ContactDR ANUP U SHELKE

DR HSRSM DENTAL COLLEGE AND HOSPITAL, HINGOLI

dranup001@gmail.com9890395919

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026