FindTrial
Sign In

Relationship between markers of inflammation and pain following a major surgery

Correlation of inflammatory cytokine, tumour necrosis factor alpha (TNF - a) and its receptor (TNF RII) with acute postoperative pain in major elective abdominal surgeries - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/03/064167
Enrollment
88
Registered
2024-03-14
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: nil: nil

Sponsors

Jawaharlal Nehru Medical College Aligarh Muslim University Aligarh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Weight between 40 – 80 kg ASA grade I to III

Exclusion criteria

Exclusion criteria: 1.Patient who is not giving consent. 2.Patients with mental dysfunction or cognitive deficiency. 3.Patients suffering from diseases known to affect TNF levels, e.g. DM. 4.Patients with neuro-muscular, vestibular, hepatic or major systemic disease. 5.History of psychiatric illness, alcohol or drug abuse 6.Patients requiring postoperative ventilatory support and intensive care management.

Design outcomes

Primary

MeasureTime frame
Inflammatory markers levels(TNF alpha, TNF alpha receptor 2) and postoperative NRS scoreTimepoint: Postoperative day 1 and 2—

Secondary

MeasureTime frame
N/ATimepoint: N/A—

Countries

India

Contacts

Public ContactQazi Ehsan Ali

Jawaharlal Nehru Medical College, Aligarh Muslim University

qaziehsanali@gmail.com7417701769

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026