A comparative study of 0.5% ropivacaine with combination of 0.5% bupivacaine and 2% lidocaine on intraocular pressure before and after peribulbar block in cataract surgery

A comparative study of efficacy and safety of single drug 0.5% Ropivacaine on intraocular pressure before and after peribulbar block in cataract surgery with most commonly used mixture of 0.5% bupivacaine and 2% lidocaine with adrenaline : A randomised clinical trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/064131

Enrollment

Registered

2024-03-14

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H251- Age-related nuclear cataract Health Condition 2: H251- Age-related nuclear cataract

Interventions

Intervention1: Injection ropivacaine 0.5%: In one group - 8ml injection ropivacaine 0.5% as local anesthesia in peribulbar block in cataract surgery Control Intervention1: Mixture of 0.5% bupivacaine

Eligibility

Inclusion criteria

Inclusion criteria: 1)Uncomplicated cataract. 2)Normal intraocular pressure

Exclusion criteria

Exclusion criteria: 1)Patients with cognitive impairment. 2)Patients allergic to hyaluronidase, lidocaine, ropivacaine and bupivacaine. 3)Any other surgeries combined with cataract. 4)Patients with hypertension and coronary artery disease in lignocaine group.

Design outcomes

Primary

Measure	Time frame
1)The study will help us to study the adverse effects caused by raised intra ocular pressure post peribulbar block and reduce the side effects caused by prolonged motor blockade by using a low concentrated anesthetic. 2)This study will help us to know an ideal drug for peribulbar block with minimal complications. Timepoint: 31 cases in 6months and total 62 cases in 1 year	—

Secondary

Measure	Time frame
This study will help us to know an ideal drug for peribulbar block with minimal complications. Timepoint: 31 cases in 6months and total 62 cases in 1 year	—

Countries

India

Contacts

Public ContactDr Rekha R Mudhol

SHRI B.M.PATIL MEDICAL COLLEGE HOSPITAL AND RESEARCH CENTRE

snehachowdary972@gmail.com9490941909

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026