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Compaison between two drugs,magnesium sulphate and ropivacaine as nebulization to facilitate endotracheal intubation in general anesthesia

To comapre the effect of magnesium sulphate versus ropivacaine nebulization in patients undergoing endotracheal intubation under general anesthesia - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/03/064129
Enrollment
70
Registered
2024-03-14
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Ropivacaine: To compare effect of Ropivacaine Nebulization 0.25%(5ml) 20 minutes before induction for 10-15minutes Control Intervention1: MAGNESIUM SULPHATE: To compare effect of Magne

Sponsors

Teerthanker Mahaveer Medical College Moradabad
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients of American society of Anesthesiologists 1 and 2,Undergoing elective surgery under general anesthesia with endotracheal intubation

Exclusion criteria

Exclusion criteria: History of recent respiratory infections, Patient using steroids, Hypersensitivity to drugs, Pregnancy, Anticipated difficult airway

Design outcomes

Primary

MeasureTime frame
Each participant in the study will be assessed for following Primary outcome parameters are as follows:- 1.To compare the severity of post operative sore throat. Timepoint: Each participant in the study will be assessed for following Primary outcome parameters are as follows:- 1.To compare the severity of post operative sore throat. Parameters recorded at after extubation in PACU( at o hour),at 2 hr,4hr,8hr,12hr and after 24 hour—

Secondary

MeasureTime frame
Each participant in the study will be assessed for following Secndary outcome parameters are as follows To compare the effect of preoperative nebulization on hemodynamic response to intubation in both the groups. To compare the effect of preoperative nebulization on hemodynamic response to extubation in both the group.  To compare effects of post operative cough & hoarseness in both the groups. To record complications if any.Timepoint: Will be nebulised 20 minutes before surgery & Haemodynamic parameter will be assessed baseline & after nebulization in preoperatively After induction Hemodynamic parameter will be assessed intraoperatively after induction at 5min & then every 10min till the extubation at 5min & 10min post extubation Post operative cough recorded in PACU 0 Hour at 2hr at 4 hr at 8 hr at 12 hr at 24hr—

Countries

India

Contacts

Public ContactDr Md Shahbaz Alam

Teerthanker Mahaveer Medical College and Research Centre

drpallaviahluwalia@yahoo.com8218628850

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026