Health Condition 1: C71- Malignant neoplasm of brain
Conditions
Interventions
Control Intervention1: NA: NA
Sponsors
Dr ARPITA SAHU
Eligibility
Inclusion criteria
Inclusion criteria: Patients with histologically proven higher grade gliomas who underwent treatment (chemotherapy, radiotherapy or both) and having suspicion for tumor recurrence or radiation necrosis.
Exclusion criteria
Exclusion criteria: 1. Patients with non-glial tumors on histology. 2. Patients who do not have tissue diagnosis or are lost on imaging follow up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.To assess the utility of Arterial Spin Labeling (ASL) in brain tumor protocol for distinguishing tumor recurrence from radiation necrosis in treated cases of grade 3 and 4 gliomas.Timepoint: Project time is 3 years. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To compare findings of perfusion i.e.Arterial Spin Labeling (ASL) and Dynamic Susceptibility Contrast (DSC) MRI. 2. Quantitative analysis of ASL, DSC findings. 3. Qualitative analysis of ASL and DSC perfusion maps. 4. To assess anyaltered signal by other MR sequences – T1W, T2W, T1 FLAIR, Post contrast T1, Post contrast T2 FLAIR, Diffusion weighted imaging, Spectroscopy. 5. Comparison of MRI results with amino acids.Timepoint: Project time is 3 years. | — |
Countries
India
Contacts
Public ContactDr SATISH KUMAR MAHAPATRA
TATA MEMORIAL HOSPITAL, MUMBAI
Outcome results
None listed