Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Spinal Anaesthesia: Neuraxial anaesthesia with Hyperbaric Levobupivacaine
Control Intervention1: adjuvants: Intravenous 0.2ml of 50% preservative free magnesium sulfate(100mg)and 5mcg d
Sponsors
Sri Guru Ram Das Institute of Medical Sciences and research
Eligibility
Inclusion criteria
Inclusion criteria: 1.American Society of Anesthesiology (ASA) Grade I and II 2. Patients who are consenting for the study 3.Patients undergoing lower gynaecological surgeries
Exclusion criteria
Exclusion criteria: 1. Contraindications to regional anesthesia such as anatomic disorders of spine, shock ,local site infections, peripheral neuropathy. 2.Pregnant female 3. Patients with the history of neuropsychiatric problems 4. Patients with communication problems that will not able to understand visual analogue scale (VAS). 5.Patients with hypersensitivity to study drugs . 6.Patients with coagulation disorders and bleeding disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of Post-operative analgesia with dexmedetomidine and magnesium sulfate as adjuvants with 0.5% hyperbaric levobupivacaine in spinal anesthesia.Timepoint: From start of surgery to 24 hours post operative | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To evaluate time of onset and duration of sensory and motor block of dexmedetomidine. 2. To evaluate time of onset and duration of sensory and motor block of magnesium sulfate. 3. To evaluate hemodynamic stability with dexmedetomidine and magnesium sulfate. Timepoint: From start of surgery to 24 hours post operative | — |
Countries
India
Contacts
Public ContactDr Deepali
Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar
Outcome results
None listed