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Which drug is better in in preventingpost operative sore throat by giving preoperative nebulisation with Dexamethasone, Ketamine and Magnesium sulphate

Comparison of preoperative nebulization of Dexamethasone,Magnesium Sulphateand Ketamine for prevention of Post operative sore throat in patients undergoing surgeries in prone position - NIL

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/03/064001
Enrollment
120
Registered
2024-03-12
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J399- Disease of upper respiratory tract, unspecified

Interventions

Intervention1: preoperative nebulisation in a patients undergoing surgeries in prone position: selescted patients were preoperative nebulisation with dexamethasone , magnesium sulphate, and ketamine f

Sponsors

Dr Bheemanna S Sinnur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: patients of both sexes with ASA grade 1&2 patients with BMI more than 18 and less than 24 patients with Mallampati grade 1&2 surgeries lasting less than 3 hours in prone position

Exclusion criteria

Exclusion criteria: lower or upper respiratory tract infection,asthma,copd pregnant women known allergies to study drug, patients on chronic medications such as nsaids and steroids

Design outcomes

Primary

MeasureTime frame
To compare and assess incidence and severity of post extubation sore throat among the three nebulized medications such as Dexamethasone, Magnesium sulphate and KetamineTimepoint: Assessed effects at 0,6,12,24 hours post extubation

Secondary

MeasureTime frame
To Assess post operative hoarseness of voice,post operative cough, incidence of pain during swallowing, To Assess side effects such as post operative nausea vomiting respiratory depressionTimepoint: Assessed at 0,6,12,24 hours post extubation

Countries

India

Contacts

Public ContactDrJyothi B

karnataka institute of medical sciences hubballi

drjyothib1@gmail.com9886187056

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026