Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Intraoperative esmolol infusion: Group E (Esmolol group): Patients in the Esmolol group will receive an IV bolus of esmolol (0.5 mg/kg) i.e 10mg/ml esmolol at a rate of 0.05ml/kg for 10
Sponsors
Sir Gangaram Hospital
Eligibility
Inclusion criteria
Inclusion criteria: ASA 1 ,2 BMI 18.5-35 Abdominal wall defect size more than 2 cm. in which autofixation device and mesh fixation will be required
Exclusion criteria
Exclusion criteria: Preoperative bradycardia History of chronic opioid use for more than 90 days Patient previously on Beta blocker Patient having received analgesics in preceding 12 hours of surgery HISTORY OF ALLERGY TO MEDICATIONS TO BE USED IN THE STUDY HISTORY OF BRONCHIAL ASTHMA OR AIRWAY HYPER REACTIVITY DECOMPENSATED LIVER,CARDIAC,RENAL OR ENDOCRINE DISEASE REFUSAL TO GIVE CONSENT FOR PARTICIPATION
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fentanyl citrate consumptionTimepoint: first 24 hours after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| rescue fentanyl citrate consumption, Pain score, Intraoperative hemodynamic instability, Postoperative sedationTimepoint: at 30 minutes, 1 hour, 2 hours, 6 hours, 12 hours and 24 hours post-operatively. | — |
Countries
India
Contacts
Public ContactDr. Anil Kumar Jain
Sir Gangaram Hospital,New Delhi
Outcome results
None listed