Comparing use of Tablet Tamsulosin with a combination of Tamsulosin and Deflazacort for clearance of ureteric stones less than 8 mm.

Tamsulosin alone and in combination with Deflazacort for medical expulsion therapy of distal ureteric calculus (less than 8mm): a randomized control study - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/063952

Enrollment

132

Registered

2024-03-11

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N201- Calculus of ureter

Interventions

Intervention1: Tamsulosin + Deflazacort: Tamsulosin 0.4 mg PO with Deflazacort 30 mg PO both once daily dose at night for 2 weeks for expulsion of distal ureteric calculus 8 mm in size Control Inte

Eligibility

Inclusion criteria

Inclusion criteria: 1) All patients who report to emergency/ Urology OPD with ureteric calculi 8 mm or less in size 2) Willing to consent for the study

Exclusion criteria

Exclusion criteria: Patient with urinary tract infection based on urine routine analysis and fever Uncontrolled pain Impaired kidney function Serum creatinine more than 1.4 mg/dl Solitary kidney

Design outcomes

Primary

Measure	Time frame
To assess stone expulsion rates on treatment with alpha blockers (Tamsulosin) and in combination with corticosteroids (Tamsulosin and Deflazacort) in patients diagnosed with distal ureteric calculus (less than 8mm)Timepoint: Stone expulsion rate assessed at 2 weeks or when patient gives history of passage of stone whichever is earlier	—

Secondary

Measure	Time frame
To assess stone expulsion rates on treatment with alpha blockers Tamsulosin alone and in combination with corticosteroids Tamsulosin and Deflazacort in patients diagnosed with ureteric calculus less than 8mm at 2 weeks To assess stone expulsion based on size of stone less than 5mm and between 5 to 8 mm Quantification of Analgesics using analgesic quantification score Average time of stone clearance on NCCT KUB on history of passage of stone or at 02 weeks whichever is earlier Timepoint: 2 weeks	—

Measure

Time frame

To assess stone expulsion rates on treatment with alpha blockers Tamsulosin alone and in combination with corticosteroids Tamsulosin and Deflazacort in patients diagnosed with ureteric calculus less than 8mm at 2 weeks To assess stone expulsion based on size of stone less than 5mm and between 5 to 8 mm Quantification of Analgesics using analgesic quantification score Average time of stone clearance on NCCT KUB on history of passage of stone or at 02 weeks whichever is earlier Timepoint: 2 weeks

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Countries

India

Contacts

Public ContactSunil Pillai

Kasturba medical college

sunil.pillai@manipal.edu9731855209

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026