Health Condition 1: K929- Disease of digestive system, unspecified
Conditions
Interventions
Intervention1: To study the effects of premedication with nebulised dexmedetomidine on blunting the haemodynamic response to laryngoscopy and tracheal intubation.: Group D: Patient will be administere
Sponsors
Department of Anaesthsia
Eligibility
Inclusion criteria
Inclusion criteria: Patients of ASA 1 and 2 undergoing general surgery under general anaesthesia requiring tracheal intubation.
Exclusion criteria
Exclusion criteria: 1) patients with body mass index more than 35 kg per meter square 2) patients with increased risk of aspiration of gastric contents 3) patients with airway difficulty score more than 8 4) patients with upper respiratory tract infection 5) patients with hepatic or renal insufficiency 6) patients with history of smoking or exposure to household smoke 7) patients taking medications which affect heart rate or blood pressure 8) pregnant patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemodynamic (heart rate, Blood pressure) response to laryngoscopy and tracheal intubationTimepoint: Hemodynamic (heart rate, Blood pressure) before nebulization (baseline), after nebulization, immediately after intubation, 1 minute after intubation, 5 minutes after intubation, 10 minutes after intubation, and at the end of surgery. | — |
Secondary
| Measure | Time frame |
|---|---|
| incidence of postoperative sore throat.Timepoint: at the end of surgery and 30 minutes after the end of surgery;The dose requirement of propofol for induction of anaesthesia to achieve target entropyTimepoint: prior to and during induction of anaesthesia | — |
Countries
India
Contacts
Public ContactLakesh Kumar Anand
MM Institute of Medical Science and Research, Mullana, Ambala
Outcome results
None listed