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Comparison between two different drug namely Dexmedetomidine and Buprenorphine for efficacy and analgesia when given as a additive to spinal anaesthesia

COMPARATIVE STUDY BETWEEN INTRATHECAL DEXMEDETOMIDINE WITH BUPRENORPHINE AS AN ADJUVANT TO ROPIVACAINE FOR INFRAUMBILICAL SURGERY.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/03/063937
Enrollment
72
Registered
2024-03-11
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: spinal anaesthesia: We propose to conduct a study by using 0.75% hyperbaric ropivacaine( 3ml) with 60 mcg of buprenorphine and 3 ml of 0.75% hyperbaric ropivacaine with 5 mcg of dexmeto

Sponsors

Indira Gandhi Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA physical status I & II Age- 18-60 years Sex- both male and female Patients undergoing elective infra umbilical surgery under spinal anaesthesia

Exclusion criteria

Exclusion criteria: ? Patients with known contraindication for spinal anaesthesia. Patients with coagulation disorders or on anticoagulation therapy. Patients with cardiac disease, nuerological.hepatc and renal impairment. Patients with betablockers & alpha antagonists.

Design outcomes

Primary

MeasureTime frame
two group has been taken group B will receive 0.75% isobaric ropivacaine 3ml with 60 mcg of buprenorphine in spinal anaesthesia. Group D will receive 0.75% isobaric ropivacaine 3ml with 5 mcg of dexmedetomidine in spinal anaesthesia.we will compare the effects on spinal block, time for rescue analgesia, and adverse effectsTimepoint: Vital sign will be recorded at every 10 minutes in operation theatre and every 15 minutes in post anaesthesia care unit—

Secondary

MeasureTime frame
1) Time of onset of sensory and motor block 2)Duration of sensory and motor block. 3) Duration of postoperative analgesia . 4) Peroperative and postoperative hemodynamic changes and side effectsTimepoint: 1.To estimate the time of onset of sensory and motor block at every 5 minutes 2.To compare the duration of sensory and motor block at every 30 minutes 3.To assess the duration of postoperative analgesia obtained in both groups at every 30 minutes 4.To describe peroperative and postoperative hemodynamic changes and side effects at every 15 minutes—

Countries

India

Contacts

Public ContactNazia Tarannum

Indira Gandhi Institute Of Medical Sciences

drswatisingh21@gmail.com6200797528

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026