None listed
Conditions
Interventions
Intervention1: NIL: nil
Sponsors
Jawaharlal Nehru Tropical Botanic Garden and Research Institute JNTBGRI
Eligibility
Inclusion criteria
Inclusion criteria: 1. Willing to sign consent form 2. Men and Women aged 40 years or greater and not older than 65 years. 3. Participant has a good understanding of the procedures of the study and agrees to abide to these 4. Participant is able to communicate well with the investigator, and attend the laboratory for all aspects of the laboratory studies 5. Participant has no known history of skin allergies or hypersensitivity to topical creams 6. Participant agrees to a pre-trial skin reactivity test for all the repellents that will be used in the trial 7. Participant agrees not to use any perfumed or scented product, including bathing products, for a 24-hour period before each laboratory session 8. Participant has signed informed consent 9. Participant is not a smoker, and will agree to refraining from smoking for the 12 hours before each laboratory trial
Exclusion criteria
Exclusion criteria: 1. Subjects with known allergy to any of the ingredients of the drug product. 2. Pregnant or Lactating women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To measure the protective efficacy (personal protection) of a plant essential oil, by comparison of the inhibition of mosquito contacts on participants before and after their application.Timepoint: After the application of essential its repellent efficacy will be observed after 15 min, then 30 min followed by 45 minutes. After wards its efficacy will be observed after 1 hour of application. Finally, the repelling efficacy will be observed after 6 h. This is well accepted procedures by WHO for testing the efficacy of mosquito repellents. WHO- GUIDELINES FOR EFFICACY TESTING OF MOSQUITO REPELLENTS FOR HUMAN SKIN | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To compare the duration of protection offered by different repellent products using the median Complete Protection Time (mCPT) 2. To compare the effectiveness of protection offered by different repellent products 3. To assess the acceptability of the repellent products tested in the field trials using qualitative data from participants.Timepoint: After the application of essential its repellent efficacy will be observed after 15 min, then 30 min followed by 45 minutes. After wards its efficacy will be observed after 1 hour of application. Finally, the repelling efficacy will be observed after 6 h. This is well accepted procedures by WHO for testing the efficacy of mosquito repellents. WHO- GUIDELINES FOR EFFICACY TESTING OF MOSQUITO REPELLENTS FOR HUMAN SKIN | — |
Countries
India
Contacts
Public ContactDr Shan Sasidharan
Pankajakasthuri Herbal Research Foundation
Outcome results
None listed