A pilot trial to study role of mastic gum in treatment of Helicobacter pylori treatment

Mastic gum as an adjunct therapy for Helicobacter pylori eradication: A randomized single-blind pilot study - nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/063908

Enrollment

Registered

2024-03-11

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K297- Gastritis, unspecified

Interventions

Intervention1: mastic gum along with standard therapy: capsule mastic gum (Pistacia Lenticus) 500 mg twice daily for 14 days along with standard Bismuth Quadruple therapy for 14 days Control Intervent

Eligibility

Inclusion criteria

Inclusion criteria: Patients with treatment naïve Helicobacter pylori infection

Exclusion criteria

Exclusion criteria: Patients with prior Helicobacter pylori treatment Patients with active gastrointestinal bleeding Use of antibiotics within one month before screening Patient who underwent upper gastro intestinal surgeries Pregnant and lactating women Patients with major systemic illness.

Design outcomes

Primary

Measure	Time frame
negative Urea breath test after 4 to 6 weeks of completion of therapy in both armsTimepoint: negative Urea breath test after 4 to 6 weeks of completion of therapy in both arms	—

Secondary

Measure	Time frame
1. symptomatic improvement using Dyspepsia Symptom Severity Index (DSSI) score in both arms 2. To compare side effect profile and compliance in both armsTimepoint: at 2 weeks, 4 weeks and 6 to 8 weeks of therapy	—

Countries

India

Contacts

Public ContactDr Ravi Kant

All India Institute of Medical Sciences, Rishikesh

drkantr2006@gmail.com9870717859

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026