comparison of a new ventilation mode with conventional mode in patient requiring post operative ventilatory support after major abdominal surgery

Comparison between Adaptive Support Ventilation and Traditional modes of mechanical ventilation SIMV combined with PSV in patients requiring postoperative elective ventilation after major abdominal surgeries a randomized controlled study. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/063874

Enrollment

Registered

2024-03-08

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K319- Disease of stomach and duodenum, unspecified

Interventions

Intervention1: group 2 simv combined with psv mode: All enrolled patients After the completion of surgery will be transferred to the ICU with tracheal intubation. simv combines with psv mode of ventil

Eligibility

Inclusion criteria

Inclusion criteria: Age greater than 18 years All patients who have undergone abdominal surgeries of duration more than 3 hrs under GA and requiring post operative mechanical ventilation. BMI less than 40 Kg per m2 ASA Grade I and II

Exclusion criteria

Exclusion criteria: Patients with obstructive or restrictive pulmonary disease Patients for re exploration surgeries Patient with Ejection fraction less than 30 percent Patient with gross electrolyte disturbance Patient with severe bleeding episode during surgery

Design outcomes

Primary

Measure	Time frame
To measure and compare the duration of mechanical ventilation in patients undergoing elective abdominal surgeries on adaptive supportive ventilation and conventional modes of ventilation ie SIMV ModeTimepoint: 1st Point: Intubation in OT 2nd Point: End of Surgery which will indicate total duration of Surgery as end point in OT 3nd Point: Transfer in ICU. 4th Point: Removal of ET Tube ie Weaning. Duration of ventilation will be difference between admission time in ICU and extubation time ie known as weaning time from the entry into ICU	—

Measure

Time frame

To measure and compare the duration of mechanical ventilation in patients undergoing elective abdominal surgeries on adaptive supportive ventilation and conventional modes of ventilation ie SIMV ModeTimepoint: 1st Point: Intubation in OT 2nd Point: End of Surgery which will indicate total duration of Surgery as end point in OT 3nd Point: Transfer in ICU. 4th Point: Removal of ET Tube ie Weaning. Duration of ventilation will be difference between admission time in ICU and extubation time ie known as weaning time from the entry into ICU

—

Secondary

Measure	Time frame
To measure the rate of extubation failure To measure the duration of ICU stay To compare the Tidal Volume, RR, Peak Inspiraotry Pressures, Peak Airway pressure at the time of randomisation versus just before extubation. To measure the PaO2 and FiO2 ratio just before and one hour after extubation To measure and compare the lactate levels one hour post extubation Timepoint: 1.5 years	—

Countries

India

Contacts

Public ContactDr Umesh Kumar Bhadani

AIIMS PATNA

umeshbhadani@gmail.com8969169123

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026