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Impact of nerve blocks on stress respone in diabetic patients undergoing laparoscopic cholecystectomy.Randomised Controlled feasibility study

Impact of Opioid free Anaesthesia (OFA) using Erector spinae block (ESB) with General Anaesthesia on stress response in Diabetic patients undergoing Laparoscopic cholecystectomy versus Opioid inclusive General Anaesthesia: A Randomised Controlled feasibility study - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/03/063861
Enrollment
80
Registered
2024-03-08
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K80- Cholelithiasis Health Condition 2: O- Medical and Surgical Health Condition 3: E119- Type 2 diabetes mellitus without complications

Interventions

Intervention1: Erector spinae block: Ultrasound guided erector spinae block will be administered with 15 ml of 0.25% Bupivaciane bilaterally Intervention2: erector spinae block: single shot, ultrasoun

Sponsors

Dr Bhargavi Sanket
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Adult diabetic patients 2. Patients willing to give informed consent 3. Patients undergoing elective laparoscopic cholecystectomy under general anaesthesia 4. Normal blood investigations 5. ASA-11 patients

Exclusion criteria

Exclusion criteria: 1. Patients with poorly controlled diabetes mellitus 2. Patients on long term opioid use, psychiatric medications 3. Patients with chronic cancer pain, chronic abdominal symptoms, immunocompromised patients, alcoholics, smokers, drug abusers, tobacco chewers. 4. contraindications for erector spinae block like infection at injection site, allergy to local anaesthetics, coagulopathies. 5. Patient not giving written informed consent

Design outcomes

Primary

MeasureTime frame
blood glucose levels serum cortisol C reactive protein epinephrine Timepoint: Baseline (0hours), 6,24,48 hours

Secondary

MeasureTime frame
Heart rate, blood pressure, oxygen saturation and visual analogue score( VAS)Timepoint: Heart rate, blood pressure, oxygen saturation with berecorded at baseline and every 15 minutes intraoperatively Post operatively, Heart rate, blood pressure, oxygen saturation, VAs will be recorded at 0,2,4,6,12,24,48 hours

Countries

India

Contacts

Public ContactDr Bhargavi Sanket

Bangalore Medical College and Research Institute, Bangalore

bhargavi_doc@yahoo.com988684323

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026