To compare the pain score after operation in patients undergoing laminectomy surgeries by spraying buprenorphine and saline in epidural space

A RANDOMIZED DOUBLE BLINDED COMPARITIVE STUDY OF INSTILLATION OF BUPRENORPHINE VS PLACEBO IN EPIDURAL SPACE FOR POSTOPERATIVE ANALGESIA IN POST LAMINECTOMY PATIENTS - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/063857

Enrollment

Registered

2024-03-08

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G952- Other and unspecified cord compression

Interventions

Intervention1: Inj Buprenorphine: 300mcg, Diluted to 10ml Instilled into epidural space, 3 mins Control Intervention1: Placebo (Normal saline): 10ml, instilled into epidural space, 3 mins

Eligibility

Inclusion criteria

Inclusion criteria: Patients willing to give informed and written consent ASA physical status I & II Patients with body weight 50-80kgs

Exclusion criteria

Exclusion criteria: ASA physical status III and above. Patients who have known hypersensitivity to the study drugs Patients with history of neuromuscular disease Patients with history of substance abuse

Design outcomes

Primary

Measure	Time frame
Pain by Numerical pain rating scale Timepoint: 1st, 2nd, 3rd, 4th, 5th, 6th, 12th, 18th and 24 hours	—

Secondary

Measure	Time frame
Pulse Rate Mean Arterial Pressure Respiratory Rate SpO2 Timepoint: 1st, 2nd, 3rd, 4th, 5th, 6th, 12th, 18th and 24 hours	—

Countries

India

Contacts

Public ContactDr Amrutha H A

BGS Global Institute of Medical Sciences

drchandana.chandana@gmail.com9980933692

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026