Health Condition 1: B978- Other viral agents as the cause ofdiseases classified elsewhere Health Condition 2: B348- Other viral infections of unspecified site Health Condition 3: O85- Puerperal sepsis Health Condition 4: A419- Sepsis, unspecified organism Health Condition 5: B999- Unspecified infectious disease
Conditions
Interventions
Intervention1: High dose vitamin C infusion in patients of sepsis: The patient of this group will receive 2.5 gram vitamin C, 8 hourly( total dose 7.5 gram/day) for 5 days as an intavenous infusion mi
Sponsors
Uttar Pradesh University of medical sciences saifai etawah
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients with body mass index between 18 to 30 2.Patient who will not be on mechanical ventilator but fulfilling the criteria of sepsis at the time of inclusion for study 3.Patient who will be on standard treatment with similar antibiotics 4.Patient with SOFA score more than 2 but less than 8 will be included in the study.
Exclusion criteria
Exclusion criteria: 1.Pregnant or breastfeeding females 2.Moribund and not expected to survive 96 hours 3.Cancer as the cause of sepsis 4.Patients with chronic kidney disease, chronic alcoholics and immuno-compromised patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the SOFA (Sequential Organ Failure Assessment) score.Timepoint: 6 days | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Incidence of ventilator associated pneumonia (VAP) if patient requires mechanical ventilation after inclusion in study. 2. Duration of vasopressor therapy 3. CRP levels 4. Length of hospital stay 5. Mortality 6. Serious adverse events like ARDS, pulmonary embolism.Timepoint: 6 days | — |
Countries
India
Contacts
Public ContactDr Sonali Agrawal
Uttar Pradesh University of medical sciences Saifai Etawah
Outcome results
None listed