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Assessment of neurocognitive functions in Parkinson patient who are ready for deep brain stimulation procedure as cases and similar assessment in controls who are waitlisted or refused Deep brain stimulation

A case control study of change in cognitive functioning after Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson’s Disease - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/03/063848
Enrollment
40
Registered
2024-03-08
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G20- Parkinsons disease

Interventions

Intervention1: NIL: NIL Control Intervention1: No intervention: No intervention

Sponsors

AIIMS New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)Diagnosis of idiopathic PD 2)Patient on 4 years of dopamine therapy 3)Motor fluctuations and drug-related Dyskinesias 4)IQ Cut Off more than or equal to 84, based on CPM 5)Willing to give written informed consent 6)Absence of dementia or severe cognitive impairment (HMSE score more than 23)

Exclusion criteria

Exclusion criteria: 1)Leads removed due to infection, malfunction, etc. 2)Suffering from any other severe psychiatric disorder (based on clinical assessment) or substance use disorder (except caffeine & nicotine) assessed through clinical interview 3)Comorbid neurological illness (e.g., stroke, TBI, SOL) 4)Uncontrolled medical illness (e.g., diabetes, hypertension) 5)Currently receiving any form of Cognitive rehabilitation Therapy

Design outcomes

Primary

MeasureTime frame
change in cognitive functions using scale - (ACE-III ),(HMSE) (IADL) (CPM) (JM-MIDI) (UPDRS) (PDQ-39) Timepoint: At baseline and After 6 months follow up

Secondary

MeasureTime frame
Change in cortical activity by using fNIRSTimepoint: At baseline and after 6 months follow up

Countries

India

Contacts

Public ContactRohit Verma

All India Institute of Medical Sciences

drvaibhavp317@gmail.com9968721083

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026