The study compares using brain activity measurements and the loss of verbal response to decide how much propofol should be given for anesthesia in adult patients undergoing elective surgeries. The research randomly assigned participants to different groups.

“Comparison of electroencephalogram entropy versus loss of verbal response to determine the dosage of propofol for induction of general anaesthesia in adult patients undergoing elective surgeries ? A randomised controlled study. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/063833

Enrollment

Registered

2024-03-08

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Entropy monitoring: Entropy monitoring, a combination of EEG and EMG measurements, will be used to assess the depth of anesthesia during the study. This involves applying a self-adhesiv

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age 18 to 60 YEARS 2. Patient willing to give informed consent and procedure as per the declaration of Helsinki guidelines 3. American society of Anesthesiologist Physical Status : ASA 1,2 in patients undergoing elective surgeries under general anaesthesia.

Exclusion criteria

Exclusion criteria: 1. Patients with severe cardiac disease, liver diseases and renal dysfunction. 2. Patients not willing to give informed consent. 3. Emergency procedures. 4. Patients with hearing disorders.

Design outcomes

Primary

Measure	Time frame
1.The dose of propofol required for induction of general anesthesia, as determined by EEG entropy and loss of verbal response.Timepoint: during induction of anaesthesia	—

Secondary

Measure	Time frame
2. Incidence of adverse events, such as hypotension, bradycardia during induction of anesthesia.Timepoint: one, five & 10 mins after induction of anaesthesia	—

Countries

India

Contacts

Public ContactRaghavendra B S

Bangalore Medical College and research institute

bsrags@gmail.com9902360703

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026