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Comparison of inflammation markers and bone loss in fluid around different dental implants over time

Comparative evaluation of inflammatory biomarkers in peri implant crevicular fluid and crestal bone loss in two different implant collar designs at different time intervals:A clinical study - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/03/063828
Enrollment
26
Registered
2024-03-08
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K056- Periodontal disease, unspecified

Interventions

Intervention1: Smooth collar design implant placement: After placement of implant, inflammatory biomarkers in periimplant crevicular fluid and crestal bone levels will be assessed at different time in

Sponsors

Dr.Paulina
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with one missing tooth in the posterior mandibular molar area Patients with good oral hygiene Patients with adequate bone height and width to accommodate implant of appropriate dimension Co-operative patient, willing to give consent

Exclusion criteria

Exclusion criteria: Patients with a known history of any systemic diseases Patients with a history of smoking Patients with a history of intake of immunosuppressive drugs, anticoagulants, and anti-cancer drugs three months prior to the study Patients with a history of radiotherapy Pregnant and lactating women

Design outcomes

Primary

MeasureTime frame
1. To evaluate the effect of Micro-Thread Collar Design on crestal bone levels and inflammatory biomarkers 2. To evaluate the effect of Smooth Collar Design on crestal bone levels and inflammatory biomarkers Timepoint: At the time of implant placement, 3 months and 6 months post-implant placement.

Secondary

MeasureTime frame
nilTimepoint: nil

Countries

India

Contacts

Public ContactDrPaulina

Manav Rachna Dental College, Faridabad

sapnarani.sds@mrei.ac.in8375899663

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026