Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: IV Drug combination (Dexket): Dexmedetomidine 0/5mic per kg and ketamine 1 mg per kg IV over 2 minutes. Hemodynamics were followed every 5 min for 30 min and hourly for 6 hours.
Interve
Sponsors
Ananta institute of medical sciences
Eligibility
Inclusion criteria
Inclusion criteria: Patients of cervical cancer scheduled for elective brachytherapy Patients aged between 20-70 years ASA I, II
Exclusion criteria
Exclusion criteria: History of cardiovascular diseases e.g. ischaemic heart disease,conduction defects, etc. History of compromised renal / hepatic / neuronal functions. Uncontrolled hypertension and Diabetes Pregnant or lactating women. History alcohol, substance abuse, chronic use of analgesic and sedatives, psychiatric disorders Patients on b blocker or having persistent bradycardia with HR30 min
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Onset and recovery of sedationTimepoint: Baseline, 1,2,5,7,10,15,20,25 and 30 minutes. | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative Haemodynamics (Heart Rate,Blood Pressure, Spo2, Respiratory rate) Post op recovery score (Modified Aldrete Score) Duration of analgesiaTimepoint: Baseline, 1, 2,5,7,10,15,20,25 & 30 minutes & then hourly for 6 hours. | — |
Countries
India
Contacts
Public ContactDr Nirdesh Thakore
Ananta institute of medical sciences
Outcome results
None listed