Role of elastography (imaging on ultrasound) in breast cancer patients recieving chemotherapy to predict responders and non responders. chemotherapy before surgery in breast cancer patients.

Role of Shear wave elastography in assessment of response to neoadjuvant chemotherapy (NACT) in breast cancer patients. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/063796

Enrollment

110

Registered

2024-03-07

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C50- Malignant neoplasm of breast

Interventions

Intervention1: Ultrasonography: 110 (sample size) breast cancer patients on neoadjuvant chemotherapy will undergo an additional ultrasonographic evaluation after 2 cycles of chemotherapy (Intervention

Eligibility

Inclusion criteria

Inclusion criteria: 1. HPR proven Operable breast cancer patients, planned for treatment (NACT + Surgery) in TMH 2. Age more than 18 years 3. Oligometastatic disease where treatment intent is curative

Exclusion criteria

Exclusion criteria: 1. Metastatic disease 2. Cystic lesion– elastography is not useful 3. DCIS with no measurable mass on USG 4. Inflammatory breast cancer 5. Pregnancy 6. Patients whose pre chemotherapy images are incomplete 7. Treatment defaulters (Patients who refuse, delay or discontinue treatment at any time point during the study) and those who receive any treatment outside TMH.

Design outcomes

Primary

Measure	Time frame
To assess role of shear wave elastography in predicting the responders vs non responders to NACT in breast cancer patients.Timepoint: 2 years	—

Secondary

Measure	Time frame
Subset analysis of different types and grades of breast cancers for response to NACT.Timepoint: 2 years;To predict pathological complete response in responders using elastography values. Timepoint: 2 years	—

Countries

India

Contacts

Public ContactDr Divyanshi

Tata Memorial Hospital, Parel

drdivyanshimahajan@gmail.com7006321268

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026