A study to compare the effectiveness of magnesium sulfate over 0.9% saline in preventing haemodynamic response associated with inflation of abdomen with carbon dioxide during laparoscopic surgeries.

Evaluate the safety and efficacy of magnesium sulfate on hemodynamic respose to pneumoperitonium in patients undergoing laparoscopic surgeries.A placebo controlled single blind randomized study - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/063795

Enrollment

Registered

2024-03-07

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Intravenous Magnesium sulfate: Frequency - Single Dose Route of Administration - Intravenous Duration of Intervention - 10 minutes before pneumoperitoneum Control Intervention1: Intrave

Eligibility

Inclusion criteria

Inclusion criteria: Eletive laparoscopic surgeries done under general anesthesia. Patients between 18 to 60 years. ASA grade I and II. Patients giving consent for study.

Exclusion criteria

Exclusion criteria: Patients not willing to participate in study Patients with hypermagnesemia. Patients with morbid obesity, severe hepatic, renal, endocrine and cardiac dysfunction. Pregnant and lactating patients.

Design outcomes

Primary

Measure	Time frame
Study the effect of magnesium sulfate on haemodynamic changes heart rate, systolic BP, diastolic BP, mean arterial pressure during laparoscopic surgeries.Timepoint: Study the effect of magnesium sulfate on haemodynamic changes heart rate, systolic BP, diastolic BP, mean arterial pressure in laparoscopic surgeries before pneumoperitoneum and every 15 minutes from pneumoperitoneum.	—

Secondary

Measure	Time frame
to assess the need for rescue drugTimepoint: during surgery	—

Countries

India

Contacts

Public ContactBINDIYA GAUTAM

DY PATIL UNIVERSITY SCHOOL OF MEDICINE NAVI MUMBAI

rpgehdoo123@gmail.com9820517674

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026