Comparation of changes in vitals and postoperative pain between 50 mcg and 100mcg spinal morphine in gynaecological oncosurgeries as add on to general anaesthesia

Comparative study of intraoperative hemodynamics and post operative analgesia between 50 mcg and 100 mcg intrathecal morphine in gynaecological oncosurgeries as adjuvant to general anaesthesia.A prospective randomised control study. - Nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/063790

Enrollment

Registered

2024-03-07

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Spinal morphine: Comparison between 50 mcg and 100 mcg morphine intrathecally Intervention2: Spinal anesthesia with morphine: Before general anesthesia patient is given 100 mcg morphine

Eligibility

Inclusion criteria

Inclusion criteria: With written valid consent ASA STATUS 1,2

Exclusion criteria

Exclusion criteria: Patient refusal Patient opioid allergy Opioid tolerance Coagulation disorders Local site infections Compromised cardiac respiratory function Severe diabetes or autonomic neuropathy On chronic pain medication Patient with comprehension disorders

Design outcomes

Primary

Measure	Time frame
1. VAS score of 4Timepoint: 1. Baseline 2.at surgical incision 3.Every 15 min from incision for 1 hr 4. Every 30 min for next 2 hrs 5.Immediate post operative 6.Pain for 4 th Hourly for 24 hours	—

Secondary

Measure	Time frame
Nausea ,vomiting Pruritis Respiratory depressionTimepoint: From time of surgical incision till 24 hours	—

Countries

India

Contacts

Public ContactAchutuni Lalitha Siva Jyothi

NIZAMS INSTITUTE OF MEDICAL SCIENCES

njonnavithula@gmail.com9849422749

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026