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Comparison of Healing after Single sitting Root canal treatment following use of different root canal irrigants in permanent molar teeth.

Effect of Final Irrigant on Healing of Periapical Lesions Following Single Visit Endodontics in Multirooted Teeth: A Randomized Controlled Trial. - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/03/063789
Enrollment
108
Registered
2024-03-07
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K045- Chronic apical periodontitis

Interventions

Intervention1: QMix 2 in 1 is used as root canal disinfectant.: 5ml of QMix 2 in 1 will be used as final irrigant for complete disinfection of root canals after mechanical root canal preparation. It w

Sponsors

All india institute of medical sciences rajkot
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 Systemically healthy individuals with age range between 18-69 years will be included 2 Necrotic, mature permanent mandibular molar teeth with periapical lesion having periapical index (PAI) score of greater than 2 and less than 5 will be included 3 Asymptomatic nonvital teeth with a negative response to electrical and cold tests and a negative response to percussion and palpation tests will be included 4 Teeth without fractures cracks or apical resorption will be included

Exclusion criteria

Exclusion criteria: 1 Patients with history of drugs antibiotics usage within the previous week 2 Patients with a history of susceptibility or adverse reactions to any drugs or materials that will be used in the study 3 Presence of calcified root canals or severe periodontal problems in the tooth in question 4 Teeth with open apex 5 Pregnant or breastfeeding women

Design outcomes

Primary

MeasureTime frame
To evaluate healing of periapical lesions following use of final irrigants using periapical Index (PAI) scoring criteria Timepoint: every 3 months till 1 year

Secondary

MeasureTime frame
Postopertaive pain evaluationTimepoint: at every 6hours for day 1 and from 2nd day each day till the 7th day

Countries

India

Contacts

Public ContactMohit Galani

AIIMS Rajkot

drmohitgalani@gmail.com8053456519

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026