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Adding additive to spinal drug to see for pain relief after surgery

Comparison of the effects of Buprenorphine and Fentanyl as intrathecal adjuvant to Hyperbaric Ropivacaine 0.75% in lower abdominal surgeries:A prospective Randomised Control Study - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/03/063780
Enrollment
60
Registered
2024-03-07
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Group F: Intrathecal fentanyl 0.2 ml with hyperbaric ropivacaine 0.75% for spinal anaesthesia in lower abdominal surgeries. Control Intervention1: Group G: Intrathecal buprenorphine 0.

Sponsors

Ananya Krishna T
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All ASA1 and 2 patients undergoing elective lower abdominal surgery under subarachnoid block.

Exclusion criteria

Exclusion criteria: All ASA 3 and 4 Patients with spinal deformity Pregnant patients Patients with height less than 140cm Patients with known drug allergy, preexisting cardiovascular, respiratory and neurological disorders Patients with local skin infections, impaired liver or renal function tests, coagulation disorders Patients with BMI more than 30kg/m2

Design outcomes

Primary

MeasureTime frame
to assess onset and duration of sensory blockade, maximum sensory blockade and the time taken for it, time taken for 2 segment regression, onset and duration of motor blockade, total duration of postoperative analgesia.Timepoint: 1,2,3,4,5,10,15,20,25,30,35,40,45,50,55,60,65,70,75,80,85,90 minutes and till 3 hours postoperative period

Secondary

MeasureTime frame
changes in heart rate, SBP,DBP,MAPTimepoint: 1, 1 1/2,2,21/2,3 hours

Countries

India

Contacts

Public ContactLakshmipriya

Mysore Medical College and Research Institute

c7drpriya@gmail.com9845099554

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026