Comparison between three intracanal dressings on pain relief in children

COMPARATIVE EVALUATION of NITROFURANTOIN,1%CHLORHEXIDINE GEL and CALCIUM HYDROXIDE as INTRACANAL MEDICAMENT on POST-OPERATIVE PAIN in PATIENTS with SYMPTOMATIC APICAL PERIODONTITIS IN PRIMARY DENTITION-A RANDOMIZED CONTROLLED TRIAL - nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/063759

Enrollment

Registered

2024-03-07

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K044- Acute apical periodontitis of pulpal origin

Interventions

Intervention1: Nitrofurantoin: 25mg of nitrofurantoin tablet mixed with 1ml of normal saline will be placed for 1 week Intervention2: Calcium Hydroxide: 100mg of calcium hydroxide is mixed with 1 drop

Eligibility

Inclusion criteria

Inclusion criteria: 1)Symptomatic Apical periodontitis in primary molars 2) Children who are rated as positive and according to the Frankl Behaviour Rating Scale (1962)

Exclusion criteria

Exclusion criteria: 1)Primary molars with grossly decayed crown structure 2)Children who have taken analgesics/anti-inflammatory drugs within the last 24 hours 3)Children with a history of allergy to any component of the local anaesthetic solution/medicament. 4)Teeth with internal root resorption

Design outcomes

Primary

Measure	Time frame
To evaluate the efficacy of nitrofurantoin as an intracanal medicament in the management of postoperative pain in symptomatic apical periodontitis To evaluate the efficacy of 1% chlorhexidine as an intracanal medicament in the management of postoperative pain in symptomatic apical periodontitis To evaluate the efficacy of calcium hydroxide as an intracanal medicament in the management of postoperative pain in symptomatic apical periodontitisTimepoint: The level of pain postoperatively is calculated at 12, 24, 48,72 hours using the Wong-Baker scale	—

Measure

Time frame

To evaluate the efficacy of nitrofurantoin as an intracanal medicament in the management of postoperative pain in symptomatic apical periodontitis To evaluate the efficacy of 1% chlorhexidine as an intracanal medicament in the management of postoperative pain in symptomatic apical periodontitis To evaluate the efficacy of calcium hydroxide as an intracanal medicament in the management of postoperative pain in symptomatic apical periodontitisTimepoint: The level of pain postoperatively is calculated at 12, 24, 48,72 hours using the Wong-Baker scale

—

Secondary

Measure	Time frame
To evaluate & compare the recorded data, i.e., the efficacy of Nitrofurantoin, 1% Chlorhexidine, & Calcium Hydroxide as an intracanal medicament in post-operative pain.Timepoint: The level of pain postoperatively is calculated at 12, 24, 48,72 hours using the Wong-Baker scale	—

Countries

India

Contacts

Public ContactShveta Sood

Manav Rachna Dental College

avantikatuli@gmail.com9634336684

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026