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Open label, Single arm, comparative study of fractional co2 and fractional co2 with tranexamic acid in Acanthosis Nigricans

A Split face comparison study of Fractional Co2 and Fractional Co2 With Tranexamic Acid In Acanthosis Nigricans - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/03/063756
Enrollment
20
Registered
2024-03-07
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L83- Acanthosis nigricans

Interventions

Intervention1: Fractional Co2 With Tranexamic Acid: On the right side of the face, tranexamic acid (500mg/5ml) will be rubbed into the skin The wavelength of 10,600nm, energy of 30-50mJ, a frequency o

Sponsors

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients diagnosed with AN of the face. 2.Age above 18 to 60 years.

Exclusion criteria

Exclusion criteria: 1.Active herpes infection 2.Keloidal tendency/ scarring post laser 3.Pregnancy 4.Uncontrolled Diabetes 5.Systemic diseases as connective tissue disease 6.History of drug intake 7.Underlying malignancy 8.History of any procedures for treatment of AN at least 1 month before enrolment.

Design outcomes

Primary

MeasureTime frame
The response to treatment will be evaluated by clinical examination and photographic comparison at baseline and during each follow up every month for 3 months post laser session.Timepoint: After 3 m onths

Secondary

MeasureTime frame
The response to treatment will be evaluated by clinical examination and photographic comparison at baseline and during each follow up every month for 3 months Acanthosis Nigricans Area and Severity Index (ANASI) Score and Acanthosis Nigricans Scoring Chart done at baseline and after 6 weeksTimepoint: After 3 months

Countries

India

Contacts

Public ContactDr Madura C

CUTIS Academy of Cutaneous Sciences

maduradr@gmail.com9632741998

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026