To assess the effect of Pistacia Lentiscus extract in Patients with Diabetic Gastroparesis

Efficacy of Pistacia Lentiscus plant extract in patients with diabetic gastroparesis –with increased small bowel transit time: A Randomized double blind control trial - Nil

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/063741

Enrollment

Registered

2024-03-06

Start date

Unknown

Completion date

Unknown

Last updated

2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E116- Type 2 diabetes mellitus with other specified complications

Interventions

Intervention1: Pistacia Lentiscus Plant Extract: This agent will be given in capsule form 500 mg per orally twice daily dose for 8 weeks time period Control Intervention1: Placebo: A similar looking c

Eligibility

Inclusion criteria

Inclusion criteria: Type 2 diabetes patients more than 18 years of age and diagnosed as Diabetic gastroparesis with increased small bowel transit time

Exclusion criteria

Exclusion criteria: Patients with age less than 18yrs Patients with any known or clinically suspected organic Gastrointestinal disorder Patients with history of gastric surgeries Patient with Irritable bowel syndrome Patients with delayed Gastric Emptying time. Patient with using drugs interfering with gastrointestinal motility

Design outcomes

Primary

Measure	Time frame
To determine the improvement in GCSI score in patients with increased Small bowel Transit Time with Pistacia lentiscus plant extracts(Chios mastic gum) in comparison with a Placebo drugTimepoint: At baseline, 2 weeks, 4 weeks, 6 weeks and 8 weeks	—

Secondary

Measure	Time frame
To calculate GCSI score pre and post intervention in both groupsTimepoint: Baseline at 0 weeks then at completion of 8 weeks;To find out the change in small intestinal transit time by using pistacia lentiscus plant extractTimepoint: AT completion of 8 weeks;To find out the effect of mastic gum on Hba1C, blood sugars, lipid profileTimepoint: Baseline data compared to data at 8 weeks;To Find the proportion of patients having Diabetic Gastroparesis by using GSCI score and Gastric Emptying ScintigraphyTimepoint: at the time of screening	—

Measure

Time frame

To calculate GCSI score pre and post intervention in both groupsTimepoint: Baseline at 0 weeks then at completion of 8 weeks;To find out the change in small intestinal transit time by using pistacia lentiscus plant extractTimepoint: AT completion of 8 weeks;To find out the effect of mastic gum on Hba1C, blood sugars, lipid profileTimepoint: Baseline data compared to data at 8 weeks;To Find the proportion of patients having Diabetic Gastroparesis by using GSCI score and Gastric Emptying ScintigraphyTimepoint: at the time of screening

—

Countries

India

Contacts

Public ContactProf Ravi Kant

AIIMS RISHIKESH

drkantr2006@gmail.com9870717859

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026