Health Condition 1: - Health Condition 2: O- Medical and Surgical
Conditions
Interventions
Intervention1: lignocaine solution: lignocaine 80 mg over glottis during intubation
Control Intervention1: oral zinc and lignocaine solution: oral zinc 40 mg 30 minutes prior to intubation and lignoc
Sponsors
NIL
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients aged 18 to 65 years. 2.Patients with American Society of Anesthesiologists (ASA) physical status [19] I to II. 3.Patients with Mallampatti grade (MPG) I & II 4.Patients scheduled to undergo elective surgery of 4 hours duration who requires general endotracheal anaesthesia.
Exclusion criteria
Exclusion criteria: 1.Patients with pre-existing steroid or non-steroidal anti-inflammatory drug use. 2.Patients who will be on Zinc supplements. 3.Patients having history of preoperative sore throat or recent upper airway infection, asthma, chronic obstructive pulmonary disease. 4.Patients with known or anticipated difficult airway. 5.Patients with known allergy to study drug. 6.Known smoker. 7.Pregnant and lactating women. 8.Patients not willing to give consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| occurrence of postoperative sore throat after tracheal extubationTimepoint: At 0 min , 1st hour , 2nd hour , 4th hour , 6 th hour and 24hrs | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Severity of postoperative sore throat. 2.Severity of post-operative cough 3.The severity postoperative hoarseness Timepoint: at 0, 1, 2, 4, 6 and 24 hours after tracheal extubation | — |
Countries
India
Contacts
Public ContactDr M Madhusudan
Sri Venkateswara Institute of Medical Sciences
Outcome results
None listed