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Effect of positive pressure on ventilator in operative period on intracranial pressure during laparoscopic gynecological surgeries.

Effect of positive end-expiratory pressure on intracranial tension during laparoscopic gynecological surgeries. A Randomised controlled trial. - Nill

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/03/063695
Enrollment
90
Registered
2024-03-06
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Effect Of Positive End-Expiratory Pressure On Intracranial Tension: T0-5 minutes after induction of general anesthesia: T1-10 minutes after patient is placed in pneumoperitoneum (PP) an

Sponsors

All India Institute Of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patient aged 18-60 years, ASA 1 and 2 scheduled for laparoscopic gynecological surgeries

Exclusion criteria

Exclusion criteria: Patient aged less than 18 and more 60 years, ASA 3 and 4, patient refusal for study, patient having previous history and ongoing ocular disease or taking medication for ocular disease, patients with neurological disease and transient ischemic attack, patient who had elevated IOP or ICP, patient who are converted to open surgery.

Design outcomes

Primary

MeasureTime frame
To compare the effect of 5 cm and 8 cm of water positive end expiratory pressure (PEEP) versus Zero PEEP (ZEEP) application on the optic nerve sheath diameter.Timepoint: Optic Nerve Sheath Diameter: T0-5 minutes after induction of general anesthesia. T1-10 minutes after patient is placed in pneumoperitoneum and change in position. T2-30 minutes after pneumoperitoneum T3-5 minutes after desufflation once patient had become supine.

Secondary

MeasureTime frame
To compare the changes in optic disc elevation with PEEP of 0 cm, 5 cm and 8 cm water.Timepoint: from 5 minutes after induction of general anesthesia to 5 minutes after desufflation once patient had become supine.

Countries

India

Contacts

Public ContactDr. Rajnish Kumar

AIIMS PATNA

drrajnishkumar@aiimspatna.org7783865337

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026