Studying how two medications, dexamethasone and ketorolac, work with levobupivacaine in a pain-relief technique called transverse abdominis plane block for women undergoing caesarean section

Comparison of dexamethasone vs ketorolac as an adjutant to levobupivacaine in ultrasound guided transverse abdominis plane block for postoperative analgesia in patients undergoing lower segment caesarean section under neuraxial anesthesia - NIL

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/063686

Enrollment

Registered

2024-03-06

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Ultrasound guided transverse abdominis plane block: Single shot injection using 0.25% levobupivacaine + 4mg dexamethasone Intervention2: Ultrasound guided transverse abdominis plane blo

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anaesthesiologists (ASA) physical status I and II, patients undergoing lower segment caesarean section, Patient’s willingness to participate in study

Exclusion criteria

Exclusion criteria: Patient’s refusal, BMI more than 35, Allergy to opioids, amide group of local anaesthetics and non steroidal anti-inflammatory drugs, Coagulation derangement or bleeding disorder, Infection at the site of block, Patients with cardiovascular pulmonary or neurological diseases, Patients converted to general anaesthesia after giving subarachnoid block, Uncontrolled intraoperative bleeding.

Design outcomes

Primary

Measure	Time frame
Compare the analgesic efficacy of dexamethasone vs ketorolac as an adjutant to levobupivacaine in ultrasound guided transverse abdominis plane block for postoperative analgesia in patients undergoing lower segment caesarean section surgeryTimepoint: Post operative VAS score in 2,4,6,12 and 24 hours. Duration of onset of pain in Hours Duration of onset of motor power in Hours.	—

Secondary

Measure	Time frame
Post operative hemodynamics , patient satisfaction score, VAS scoreTimepoint: Post operative Blood pressure and Heart rate at 2,4,6,12 and 24 hours. Patient satisfaction score after 24 hours.	—

Countries

India

Contacts

Public ContactDr Rathna

Saveetha medical college and hospital

drrathna86@yahoo.co.in9940475385

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026