Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: palanosetron75 microgram 10min prior to induction of general anaesthesia: The number of episodes of nausea, retching and vomiting and side effects if any will be assessed postoperativel
Sponsors
DR SOMSUNDAR R G
Eligibility
Inclusion criteria
Inclusion criteria: 1.Aged between 18 to 60 years 2.ASA I and II category patients 3.Patients undergoing elective otorhinolaryngology surgeries under general anaesthesia 4.Patients willing to give informed consent to participate in the study.
Exclusion criteria
Exclusion criteria: 1.Allergy to palonosetron and ondensetron 2.Use of antiemetics within 48 hours prior to surgery 3.Patient refusal 4.Patient with prolonged QT syndrome
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the efficacy of ondansetron versus palonosetron in preventing postoperative nausea and vomiting in the first 24 hours using three scoring systems (nausea score, postoperative vomiting score, and postoperative nausea and vomiting score) in patients undergoing elective otorhinolaryngology surgeries under general anaesthesiaTimepoint: at base line , 2 hours , 6 hours , 12 hours , 24 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| To measure the severity of nausea, need for rescue medication, patient’s satisfaction and incidence of adverse effects. Timepoint: 0 to 2 hrs, 2 to 6 hrs, 6 to 24 hrs | — |
Countries
India
Contacts
Public ContactDR SHARMILA SHERIN
MANDYA INSTITUTE OF MEDICAL SCIENCES
Outcome results
None listed