Effect of a drug on postoperative blood sugar

EFFECT OF A SINGLE INTRAOPERATIVE DOSE OF DEXAMETHASONE ON GLYCEMIC PROFILE IN POST OPERATIVE PATIENTS, UNDERGOING ELECTIVE LAPAROSCOPIC SURGERY UNDER GENERAL ANAESTHESIA: RANDOMISED CONTROLLED TRIAL - Nil

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/063644

Enrollment

100

Registered

2024-03-05

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K829- Disease of gallbladder, unspecified Health Condition 2: K829- Disease of gallbladder, unspecified

Interventions

Intervention1: EFFECT OF A SINGLE INTRAOPERATIVE DOSE OF DEXAMETHASONE ON GLYCEMIC PROFILE IN POST OPERATIVE PATIENTS, UNDERGOING ELECTIVE LAPAROSCOPIC SURGERY UNDER GENERAL ANAESTHESIA: In this study

Eligibility

Inclusion criteria

Inclusion criteria: The patients of aged 18-70 years with Body Mass Index (BMI) ranging from 18.5 to 24.9 kg/m2, American Society of Anesthesiologists (ASA) physical status I and non-diabetic ASA II status posted for elective laparoscopic surgery will be recruited and studied for 72 hours.

Exclusion criteria

Exclusion criteria: Candidates with preexisting diabetes mellitus (FBS more than 126 mg/dl, postprandial blood sugar (PPBS) more than 200 mg/dl, HbA1c more than 6.5), Chronic steroid therapy (taking steroid more than 10mg, for more than 10 days within last 10 months), History of allergy to dexamethasone, Pregnancy, History of peptic ulcer disease, Malignancy, Duration of anaesthesia more than 2 hours, Patients who have history of any vomiting, Retching, or nausea in the 24 hours preceding the administration of anaesthesia.

Design outcomes

Primary

Measure	Time frame
To compare the changes in the glycemic profile up to 72hours in patients receiving a single dose of dexamethasone in elective laparoscopic surgeryTimepoint: To compare the changes in the glycemic profile up to 72hours in patients receiving a single dose of dexamethasone in elective laparoscopic surgery	—

Secondary

Measure	Time frame
To compare the incidence of postoperative nausea and vomiting (PONV) And Postoperative pain in term of VAS score.Timepoint: Number of nausea and vomiting episodes will be documented 12 hourly and grading will be done accordingly. And Postoperative pain will be assessed and documented 12 hourly by using Visual Analogue Scale	—

Countries

India

Contacts

Public ContactDr Fateh Singh Bhati

Dr SN Medical College, Jodhpur , Rajasthan

fatehbhati68@gmail.com9414127176

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026