Exploring the Modulation of Plasma p-tau181 Protein in Alzheimers Disease: A Clinical Trial with Saraswata Ghrita Nasya(nasal instillation) Intervention

Modulation of Plasma phosphorylated tau181 (p-tau181) protein through Saraswata Ghrita nasya in Alzheimer’s Disease – An add on exploratory clinical trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/063642

Enrollment

Registered

2024-03-05

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G308- Other Alzheimers disease

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients between the age group of 50 to 80 years. 2. Patients of both genders. 3. Diagnosed case Diagnosed case of AD as per DSM IV criteria

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
1 Effect on clinical signs and symptoms and ADAS scale for Alzheimer’s disease patients and effect on improving quality of life of Alzheimer’s disease patients would be determined. 2 Modulatory effect of Saraswata Ghrita on the plasma expression of protein Plasma phosphorylated tau181 (p-tau181) protein of Alzheimer’s Disease patients would be evaluated. Timepoint: assessment will be at base line ie zero day and at 90th day	—

Measure

Time frame

1 Effect on clinical signs and symptoms and ADAS scale for Alzheimer’s disease patients and effect on improving quality of life of Alzheimer’s disease patients would be determined. 2 Modulatory effect of Saraswata Ghrita on the plasma expression of protein Plasma phosphorylated tau181 (p-tau181) protein of Alzheimer’s Disease patients would be evaluated. Timepoint: assessment will be at base line ie zero day and at 90th day

—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr Pramod Yadav

All India Institute of Ayurveda

drpramod88@gmail.com8930625596

Outcome results