Individualised Homoeopathic Treatment of Chronic Brucellosis in human beings along with Standard Care

Individualised Homoeopathic Treatment of Chronic Brucellosis in human beings along with Standard Care – An open-label, pragmatic, and two arm Pilot Study - NIL

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/063640

Enrollment

Registered

2024-03-05

Start date

Unknown

Completion date

Unknown

Last updated

2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A231- Brucellosis due to Brucella abortus Health Condition 2: A233- Brucellosis due to Brucella canis Health Condition 3: A230- Brucellosis due to Brucella melitensis Health Condition 4: A232- Brucellosis due to Brucella suis Health Condition 5: A239- Brucellosis, unspecified Health Condition 6: A238- Other brucellosis

Interventions

Intervention1: 1. Arsenicumalbum 2. Antim Crud 3. Bryoniaalba 4. Baptisia -T 5. Carcinosin 6. Car.V 7. Coff.cruda 8. Thuja. Occ 9. Mag M 10. Camphora 11. Ignatia 12. Rhustoxicodendron 13. Belladonna 1

to be taken orally on clean tongue with empty stomach. repetition of Homeopathic Medicines as per Homeopathic Principles Control Intervention1: Doxycycline, 200 mg, gentamicin 3–5 mg/kg/day, rifampin

Eligibility

Inclusion criteria

Inclusion criteria: •Patients aged between 18 and 60 present with clinical signs and symptoms of recurrent or chronic Brucellosis. (Chronic brucellosis refers to patients whose symptoms persist for 12 months or more from diagnosis and treatment ). •Patients willing to give informed consent.

Exclusion criteria

Exclusion criteria: •Known cases of uncontrolled diabetes hypertension. •Person with any organic changes CA and others, i.e. tuberculosis, etc. •Severe condition of the patient in any aspect of health. •Pregnant or lactating women.

Design outcomes

Primary

Measure	Time frame
symptomatic profile of the pateint will be assessed by cured,major improvemnt,moderate improvement,slight improvement,no changes,slight detioration,moderate detioration ,major detioration and diststrous detioration.MYMOP 2 tool to find the improvemnt.Timepoint: base line, Every 03 day for first 1 month(09 times),consecutively per month for next 11 months.	—

Secondary

Measure	Time frame
To assess the Quality of Life (QoL) using the EQ-5D-5L questionnaire as a parameter to compare and detect differences between two groups. This evaluation will provide valuable insights into the impact of the treatment approach on the overall well-being and quality of life of patients in each group.Timepoint: To assess the Quality of Life (QoL) using the EQ-5D-5L questionnaire EVERY MONTH, UPTO 12 TH MONTH. Using MYMOP Questionnaire every month upto 12th month. Modified Naranjo criteria every month upto 12th month	—

Measure

Time frame

To assess the Quality of Life (QoL) using the EQ-5D-5L questionnaire as a parameter to compare and detect differences between two groups. This evaluation will provide valuable insights into the impact of the treatment approach on the overall well-being and quality of life of patients in each group.Timepoint: To assess the Quality of Life (QoL) using the EQ-5D-5L questionnaire EVERY MONTH, UPTO 12 TH MONTH. Using MYMOP Questionnaire every month upto 12th month. Modified Naranjo criteria every month upto 12th month

—

Countries

India

Contacts

Public ContactDrChittaranjan Kundu

Central Council for Research in Homoeopathy

dr.kundu1984@gmail.com9474543940

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026