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Treatment of Bone Loss with Bone Graft.

Comparative evaluation of demineralized freeze dried bone allograft with and without PRF membrane in the treatment of periodontal intrabony defects. - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/03/063595
Enrollment
20
Registered
2024-03-05
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: DFDBA with PRF membrane in periodontal intrabony defects: Patients autologous blood is withdrawn and centrifuged to make PRF membrane. Changes are observed before the surgical procedure

Sponsors

Sarita Parihar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with moderate to severe periodontitis with a probing depth (PD) =5mm & Intrabony component of =3 mm as detected on IOPA x-ray & bone sounding. 2.Healthy individual willing for study with no systemic diseases that will influence the outcome of therapy. 3.Not using tobacco in any form. 4. Able to achieve good oral hygiene. 5. Subjects who gave written consent. 6. Subjects who were available for follow up

Exclusion criteria

Exclusion criteria: 1. Medically compromised patients with presence of any systemic disease. 2. Pregnant & Lactating women. 3. Patients taking any medication. 4. Teeth with one wall defects, furcation involvement & mobility. 5. Hypersensitivity or allergy to allograft based medical products.

Design outcomes

Primary

MeasureTime frame
• Changes in PPD (Periodontal Probing Depth) • CAL (Clinical Attachment Level) • Radiographic bone gain Timepoint: Baseline and after 6 months

Secondary

MeasureTime frame
Changes in position of Gingival margin Plaque Index Gingival index Timepoint: Baseline and after 6 months

Countries

India

Contacts

Public ContactSarita Parihar

Institute of Medical Sciences, Banaras Hindu University

saritaparihar@bhu.ac.in8004925677

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026