effect of two different drugs on hemodynamic stability in elective lower segment cesarean section

Comparative study between intrathecal 0.5% hyperbaric levobupivacaine and 0.5% hyperbaric bupivacaine with nalbuphine as adjuvant in elective lower segment cesarean section: A randomized clinical study - nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/063579

Enrollment

Registered

2024-03-04

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Nalbuphine: 400mcg nalbuphine intrathecally as an adjuvant Control Intervention1: Levobupivacaine & Bupivacain: 2 ml hyperbaric Inj. 0.5% levobupivacaine and 2 ml hyperbaric Inj. 0.5% b

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing elective LSCS

Exclusion criteria

Exclusion criteria: 1. Patients with cardiovascular diseases. 2. Contraindications to regional anesthesia such as local infections/sepsis at the site of lumbar puncture, anatomical disorders of spine, shock, any bleeding disorder and patient on anticoagulants. 3. Hypersensitivity to study drugs 4. History of opioid dependence 5. Fetal distress

Design outcomes

Primary

Measure	Time frame
To evaluate the effects of bupivacaine and levobupivacaine with combination of nalbuphine in terms of onset, regression and duration of sensory and motor blockade, time to requirement of first rescue analgesia for LSCS.Timepoint: till the end of surgery	—

Secondary

Measure	Time frame
1. To compare the hemodyanamic effects of bupivacaine and levobupivacaine with nalbuphine as adjuvant in elective lower segment cesarean section. 2. To evaluate the of duration of postoperative analgesia bupivacaine and levobupivacaine with nalbuphine as adjuvant in elective lower segment cesarean section Timepoint: from the initiation of anaesthesia till 24 hours	—

Countries

India

Contacts

Public ContactDr Anmol Singh

Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar

kumarianitadr1@gmail.com9815632909

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026