Study of post operative sore throat, hoarseness of voice and cough after nebulization with ketamine and magnesium sulphate in patients undergoing general anaesthesia.

A randomized double blind comparative study of incidence and severity of post operative sore throat,hoarseness of voice and cough after nebulization with ketamine and magnesium sulphate in patients undergoing general anaesthesia with endotracheal intubation. - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/063567

Enrollment

100

Registered

2024-03-04

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: nebulization with ketamine and normal saline: Incidence and severity of post operative sore throat, hoarseness of voice and cough after nebulization with ketamine 50 MG and normal sali

Eligibility

Inclusion criteria

Inclusion criteria: Patients between 18- 60 years of either sex Undergoing surgeries under general anaesthesia in supine position Duration of surgery upto 2hours ASA physical status -I & II

Exclusion criteria

Exclusion criteria: Age- 60 yrs ASA physical status III & above Mallampatti grade >2 Any psychiatric disorder and history of epilepsy Neurological patients with raised Intracranial pressure Patients with known coronary artery disease,old myocardial infarction and ischemic heart disease Pregnancy Patients sensitive or allergic to study drugs History of pre operative sore throat, oral surgeries, asthma ,chronic obstructive pulmonary disease, head and neck surgeries Recent non steroidal drugs medication Anticipated difficult intubation Patients those who will require >2attempts at intubation Patients and/ or his/her legally acceptable representative not willing to provide their voluntary written informed consent for participation in the study

Design outcomes

Primary

Measure	Time frame
incidence and severity of sore throat, hoarseness of voice and coughTimepoint: 24 hours postoperative period	—

Secondary

Measure	Time frame
haemodynamic changes, side effectsTimepoint: 24 hours post operative period	—

Countries

India

Contacts

Public ContactDr Veena Mathur

JLN Medical College, Ajmer

veenamathur41@gmail.com9460517947

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026