Comparing how Sevoflurane differs from Isoflurane on affecting post operative cognitive dysfunction after a laparoscopic cholecystectomy surgery done under general anesthesia.

Comparison of Sevoflurane and Isoflurane on post operative cognitive dysfunction following laparoscopic cholecystectomy. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/063503

Enrollment

Registered

2024-03-04

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K800- Calculus of gallbladder with acutecholecystitis

Interventions

Intervention1: Sevoflurane: After induction patient will be maintained with inhaled Sevoflurane in 1-1.5 MAC range for the duration of surgery. Control Intervention1: Isoflurane: After induction pati

Eligibility

Inclusion criteria

Inclusion criteria: 1. Those willing to give written - informed consent. 2.ASA physical status I and II patients.

Exclusion criteria

Exclusion criteria: 1. Refusal of the patient. 2. Age less than 18 years and more than 60 years. 3. Patients above ASA III grade. 4.Patients who do not speak hindi or english. 5. Patients who do not have an elementary school education.

Design outcomes

Primary

Measure	Time frame
To find out how Sevoflurane differs from Isoflurane on affecting postoperative cognitive dysfunction following a laparoscopic cholecystectomy surgery.Timepoint: until 24 hours post-extubation after the procedure.	—

Secondary

Measure	Time frame
1.To compare the incidence and severity of post operative shivering between sevoflurane and isoflurane. 2.To find out the incidence of post operative nausea and vomiting between sevoflurane and isoflurane.Timepoint: until 24 hours post-extubation after the procedure.	—

Countries

India

Contacts

Public ContactDr Barun Ram

Rajendra Institute of Medical Sciences

mukeshgmch@gmail.com7004993204

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026