Measure the endotracheal tube cuff pressure changes with use of nitrous oxide and air separately and compare them during general anaesthesia.

COMPARISON OF ENDOTRACHEAL TUBE CUFF PRESSURE CHANGES WITH USE OF NITROUS OXIDE VERSUS AIR DURING GENERAL ANAESTHESIA. - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/063462

Enrollment

120

Registered

2024-03-01

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: X- New Technology Health Condition 2: 8- Other Procedures

Interventions

Intervention1: COVIDIEN Shiley Hi - Lo hand pressure gauge manometer: This devise measure the cuff pressure changes in nitrous oxide versus air during general anaesthesia Measures at timely intervals

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA grade I and II 2.Non hypertensive 3.Non obese 4.MPC I and II 5.Surgeries lasting for at least upto 2 hours and not beyond 4 hours 6.Elective surgeries

Exclusion criteria

Exclusion criteria: 1.Refused to participate in study 2.Patients with nasogastric tube 3.Contraindication to use of nitrous oxide 4.MPC III and IV 5.Hypertensive patients 6.Asa III and more 7.Short surgeries( duration less than 2 hours) 8.Day care surgeries 9.Emergency surgeries 10.Neck surgeries involving handling of airway

Design outcomes

Primary

Measure	Time frame
Monitor changes in endotracheal tube cuff pressure changes with use of nitrous oxide at 0minutes, at 5 minutes, 10 minutes , 15 minutes , 30 minutes till 240 minutes Monitor the changes in cuff pressure in air at 0 minutes,5 minutes,10 minutes,15 minutes, 30 minutes till 240 minutes.Timepoint: Outcomes assessed by 8 weeks.	—

Secondary

Measure	Time frame
changes in endotracheal tube cuff pressure with air versus nitrous oxide at 0 minutes, 5 minutes, 15 minutes, 30 minutes.Timepoint: 8 weeks	—

Countries

India

Contacts

Public ContactAYSATH NUHAIMAH

Bjmedical college

naheemaaysha@gmail.com9422041994

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026